7:25 p.m. Thursday
Edward Jones Dome (66,000 capacity)
TV: NFL Network and KPLR-Channel 11 with Brad Nessler calling the play-by-play, Mike Mayock providing the color commentary and Alex Flanagan serving as sideline reporter.
Radio: WXOS-FM 101.1 with Steve Savard calling the play-by-play, D'Marco Farr providing the color commentary and Tony Softli serving as the sideline reporter.
Coaches: Jim Harbaugh has a 25-9-1 record in his third season as the 49ers' head coach. Jeff Fisher has a 150-129-1 record in his 19th season as an NFL head coach. He has an 8-10-1 mark in his two seasons with the Rams.
Fun Fact: In 13 career games against the Rams, 49ers wide receiver Anquan Boldin has 83 catches for 1,138 yards, his highest total against any NFL opponent.