The Yankees played home run derby Thursday, with Giambi, Johnny Damon, Robinson Cano and Wilson Betemit connecting in a 6-3 victory over the Cleveland Indians.
Mike Mussina (5-3) won his fourth straight start and earned his 255th career victory, holding on for five innings. Joba Chamberlain pitched an easy eighth and Mariano Rivera closed for his ninth save.
Cleveland was trying to sweep the Yankees in a series of three or more games for the first time in nearly two decades. The last time the Indians did, they completed by beating Tommy John on April 9, 1989 -- John, by the way, turns 65 in two weeks.
Cano's homer finished Paul Byrd (1-3) in the seventh and Betemit, subbing for the injured Alex Rodriguez, met reliever Masa Kobayashi with a drive over the center-field fence. The Yankees tied a season high with their four home runs.
Mussina moved into sole possession of 39th place on the career wins list, breaking a tie with Jack Morris and Red Faber.
White Sox 6, Twins 2
In Chicago, Jermaine Dye homered for the third straight game and Juan Uribe added a go-ahead two-run drive in the fifth for the White Sox.
John Danks (3-3) made it through five innings, giving up six hits and two runs, and Chicago won for just the second time in nine games.
Minnesota manager Ron Gardenhire returned after missing five games following the death of his brother, but his first game back was an abbreviated one. He was ejected for the 37th time in his career and first time this season in the sixth inning by plate umpire Doug Eddings after a double steal by the White Sox.
Kevin Slowey (0-2) allowed three runs and four hits in five innings for the Twins.
Red Sox 5, Tigers 1
In Detroit, Josh Beckett got eight strikeouts, including the 1,000th of his career and Kevin Youkilis hit another home run at spacious Comerica Park to lead the Boston Red Sox to a win over the Detroit Tigers.
Beckett (4-2) gave up six hits and a run in seven innings and Youkilis hit his third home run in two games, giving him eight in Detroit. He hasn't hit more than two outside Fenway Park..
Justin Verlander (1-6) gave up five runs on nine hits in six innings.
Orioles 4, Royals 1
In Kansas City, Mo., Daniel Cabrera threw a three-hitter to remain perfect against Kansas City, Nick Markakis backed him with a three-run home run, and the Baltimore Orioles snapped a five-game losing streak.
Cabrera (3-1) struck out seven and walked one in his fifth career complete game and first since Sept. 28, 2006 against the Yankees.
