The Cougars, who led just 38-36 at halftime, outscored Tennessee Tech 20-9 in the third quarter to create some breathing room and then held on in the fourth quarter.
Lauren White and Gwen Adams each scored 15 points for the Cougars, who will face seventh-seeded Eastern Kentucky at 2 p.m. Friday. Eastern Kentucky upset second-seeded Morehead State 73-67 on Wednesday.
The tournament champion earns an automatic bid into the NCAA Women’s Basketball Tournament.
The conference tournament is being televised on ESPN3 and OVCDN.